Why Culture Agitator Plays An Important Role With Dissolved Oxygen Level
Culture agitators play an important role in maintaining an adequate level of dissolved oxygen in biological systems because oxygen is essential for many biological processes, including cell growth, metabolism, and product formation. Adequate mixing and aeration are necessary to ensure that oxygen is evenly distributed throughout the culture medium and is available to the cells.
In bioprocessing applications, culture agitators are used to provide a homogeneous environment for cells and to prevent the formation of dead zones. Dead zones are areas within the culture medium where there is little or no mixing, and these areas can become depleted of oxygen, nutrients, and other essential components. Dead zones can lead to reduced cell growth and productivity, as well as the accumulation of toxic metabolites, which can further inhibit cell growth.
Culture agitators help to increase the transfer of oxygen from the air into the culture medium, which increases the dissolved oxygen level. Higher dissolved oxygen levels can promote faster cell growth, increased cell viability, and higher productivity. However, the agitation rate must be optimized to prevent excessive shear stress on the cells, which can damage or kill them.
Overall, the culture agitator is essential for maintaining an optimal level of dissolved oxygen in biological systems, which is critical for efficient and consistent bioprocessing outcomes. By providing adequate mixing and aeration, culture agitators ensure that cells have access to the oxygen and nutrients they need for optimal growth and product formation.